El Ciclo de Krebs / Rap Medicina

Krebs Cycle

rap for the faculty
medicine rap

Acetyl-CoA is condensed
And Oxaloacetate
By the enzyme Citrate Synthase, Citrate is formed
And Citrate dehydrates
Forming Cis-Aconitate by the enzyme Aconitase
And passes through the same Aconitase enzyme

Cis-Aconitate hydrates with H2O
And by hydrating, Isocitrate is formed
And an oxidation forms Oxalosuccinate
But, what was the enzyme for the oxidation? Isocitrate Dehydrogenase this time
I emphasize a fact in this action
The first 3 ATPs in this reaction

Oxalosuccinate decarboxylates, reaction
That occurs through the same enzyme
And becomes Alpha-ketoglutarate
It's not complicated, learn the cycle, novice

Alpha-ketoglutarate turns into Succinyl-CoA through oxidative decarboxylation
Enzyme that has a place in this process
Active Alpha-ketoglutarate dehydrogenase
And, in this stage of the Krebs Cycle
3 ATPs are produced again
While Succinyl-CoA forms
Succinate because it is phosphorylated
At the substrate level

When Succinyl-CoA then passes to Succinate, by the enzyme Succinyl-CoA Synthetase
An ATP is released in the process
Get to know the cycle, buddy
You know about that

Succinate goes to Fumarate
By oxidation producing 2 ATPs in release
Succinate dehydrogenase
With its introduction, was the enzyme
That had participation there

Fumarate turns into Malate when
It hydrates performing the process
By the enzyme Fumarase
And Malate is oxidized and momentarily
Passes, Malate dehydrogenase acts

Then Malate returns to Oxaloacetate, releasing 3 ATPs
In just a moment
Then the process continues
Starting from the beginning and Acetyl-CoA arrives again
And the cycle repeats